ALI |
Acute lung injury |
SIRS |
Systemic inflammatory response syndrome |
Sepsis-3 |
The publication of the third international consensus definition of sepsis and septic shock |
qSOFA |
Quick SOFA |
ARDS |
Acute respiratory distress syndrome |
TNF-α |
Tumor necrosis factor-α |
IL-1β |
Interleukin-1β |
IL-6 |
Interleukin-6 |
NF-κB |
Nuclear factor-κB |
PI3K |
Phosphatidylinositol-3 kinase |
AKT |
Protein kinase B |
MNK |
Mitogen-activated protein kinase interacting kinases |
ErK |
Extracellular signal-regulated kinase |
LPS |
Lipopolysaccharide |
PI3Kδ/γ |
Phosphoinositide 3-kinase delta/gamma pathway |
ROCK |
Rho-associated protein kinase |
Tie2 |
Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 2 |
MD2 |
Myeloid differentiation factor 2 |
TLR4 |
Toll-like receptor 4 |
TLRs |
Toll-like receptors |
TNF |
Tumor necrosis factor |
ILs |
Interleukins |
ROS |
Reactive oxygen species |
PAMPs |
Pathogen-associated molecular patterns |
DAMPs |
Damage-associated molecular patterns |
CLP |
Cecal ligation and puncture |
WT |
Wild-type |
MyD88 |
Myeloid differentiation primary response 88 |
IL-1R |
Interleukin-1 receptor |
IRAK |
IL-1R-associated kinase |
NOX |
NADPH oxidase |
O2−
|
Superoxide anion |
AMPK |
Adenosine monophosphate-activated protein kinase |
ECM1 |
Extracellular matrix protein 1 |
STAT5 |
Signal transducer and activator of transcription 5 |
NLRP3 |
Nucleotide-binding oligomerization domain-like receptor protein 3 |
TAN |
Tangeretin |
PLK1 |
Polo-like kinase 1 |
DRP1 |
Dynamin-related protein 1 |
STAT3 |
Signal transducer and activator of transcription 3 |
GSDM |
Gasdermin D |
ERRα |
Estrogen-related receptor alpha |
Pla2g2a |
Phospholipase A2 type IIA |
EGFR |
Epidermal growth factor receptor |
MUC1 |
Mucin 1 |
miR-199a |
microRNA 199a |
DHM |
Dihydromyricetin |
Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
HO-1 |
Heme oxygen-ase-1 |
ICAM |
Intercellular adhesion molecule |
iNOS |
Inducible nitric oxide synthase |
SOD |
Superoxide dismutase |
CAT |
Catalase |
NO |
Nitric oxide |
ISL |
Isoliquiritigenin |
MDA |
Malondialdehyde |
GSH |
Glutathione |
MIF |
Macrophage inhibitory factor |
JAK2 |
Janus kinase 2 |
GA |
Glycyrrhizic acid |
Rg1 |
Ginsenoside Rg1 |
AS-IV |
Astragaloside IV |
BA |
Betulinic Acid |
cAMP |
Cyclic adenosine monophosphate |
cGMP |
Cyclic guanosine monophosphate |
ER-β |
Estrogen receptor-β |
MAPKs |
Mitogen-activated protein kinases |
EPCR |
Endothelial protein C receptor |
MPO |
Myeloperoxidase |
JNK |
c-JunN-terminalkinases |
mTOR |
Mammaliantarget of rapamycin |
IKK |
Inhibitor of kappa B kinase |
VEGF |
Vascular endothelial growth factor |
AP-1 |
Activator protein-1 |
PGC-1α |
Peroxisome proliferator-activated receptor-γ coactivator 1-α |
CaMKII |
Ca2+/calmodulin-dependent protein kinase II |
MLCK |
Myocin light chain kinase |
HMGB1 |
High mobility group protein 1 |
MMP-9 |
Matrix metalloproteinase 9 |
MH-S |
Mouse alveolar macrophages |
COX-2 |
Cyclooxygenase-2 |
SMAD3 |
Mothers against decapentaplegic homolog 3 |
Bcl-2 |
B-Cell CLL/Lymphoma 2 |
Bax |
BCL2-associated X protein |
Caspase-1 |
Cysteine-requiring aspartate protease-1 |