Figure 2.

Animal welfare measures following infection of immunised NHPs. Welfare of J8-ADI (fuchsia lines) and ΔGAC-ADI (green lines) immunized NHPs during infection was monitored by veterinary staff by measuring weight change (A), rectal temperature (B) and white blood cell counts (C). Welfare measures for PBS (black lines) and M1 (red lines) immunised NHPs were previously reported [18] and are shown for comparative purposes. The temperature of M1-immunised NHPs was only measured from day 7 onwards. Lines represent the median values ± 95% CI.