Table 1.

Initial hydrodynamic size, polydispersity index, and zeta potential of blank-LNP and CBD-LNP after being kept at 4, 25, and 45 °C for 30 days.

Hydrodynamic Size (nm)	Day 0	Day 30
		Kept at 4 °C	Kept at 25 °C	Kept at 45 °C
Blank-LNP	169.93 ± 34.41	163.50 ± 3.78	151.27 ± 2.15	153.80 ± 0.44
CBD-LNP	156.33 ± 1.24	158.17 ± 1.06	167.87 ± 0.81	166.83 ± 5.37
Polydispersity	Day 0	Day 30
		Kept at 4 °C	Kept at 25 °C	Kept at 45 °C
Blank-LNP	0.41 ± 0.02	0.18 ± 0.02	0.10 ± 0.03	0.07 ± 0.03
CBD-LNP	0.11 ± 0.10	0.12 ± 0.02	0.10 ± 0.03	0.13 ± 0.02
Zeta Potential (mV)	Day 0	Day 30
		Kept at 4 °C	Kept at 25 °C	Kept at 45 °C
Blank-LNP	−3.53 ± 0.15	−15.28 ± 0.09	−17.89 ± 0.84	−13.04 ± 0.63
CBD-LNP	−16.57 ± 0.04	−17.04 ± 0.90	−14.47 ± 2.08	−19.55 ± 0.70