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. 2024 Apr 9;17(4):481. doi: 10.3390/ph17040481

Table 8.

Summary of microscopic findings during + terminal euthanasia and recovery + euthanasia.

Summary of Microscopic Findings–Terminal Euthanasia (Day 29)
Males Females
Group 1 2 3 4 1 2 3 4
Dose (mg/eye) 0 0.05 0.15 0.5 0 0.05 0.15 0.5
No. Animals per Group 3 3 3 3 3 3 3 3
Eyes (No. Examined) 3 3 3 3 3 3 3 3
 Right: Infiltration, mononuclear
    cell, vitreous chamber
(0) a 0 2 3 0 0 2 3
    Minimal Mild 0 0 2 1 0 0 2 1
    Mild 0 0 0 2 0 0 0 2
 Left: Infiltration, mononuclear
    cell, vitreous chamber
0 0 3 3 0 0 2 3
    Minimal 0 0 3 1 0 0 2 2
    Mild 0 0 0 2 0 0 0 1
a Numbers in parentheses represent the number of animals with the finding
Summary of Microscopic Findings–Recovery Euthanasia (Day 43)
Males Females
Group 1 2 3 4 1 2 3 4
Dose (mg/eye) 0 0.05 0.15 0.5 0 0.05 0.15 0.5
No. Animals per Group 2 2 2 2 2 2 2 2
Eyes (No. Examined) 2 2 2 2 2 2 2 2
 Right: Infiltration, mononuclear
    cell, vitreous chamber
(0) a 0 1 2 0 0 1 2
    Minimal Mild 0 0 1 1 0 0 1 1
    Mild 0 0 0 1 0 0 0 1
 Left: Infiltration, mononuclear
    cell, vitreous chamber
0 0 0 2 0 0 0 2
    Minimal 0 0 0 1 0 0 0 2
    Mild 0 0 0 1 0 0 0 0
a Numbers in parentheses represent the number of animals with the finding