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Antiamastigote activity of M. nervosa EO.
| EO | IC50 ±SD (μg/mL) | SP | ||
|---|---|---|---|---|
| L. major | L. infantum | L. major | L. infantum | |
| M. nervosa | 8.04 ± 0.5 | 7.32 ± 0.87 | 0.84 | 0.71 |
| AmpB | 0.72 ±0.08 | 0.43 ±0.05 | 1.34 | 1.48 |
IC50: 50% inhibitory concentration; LC50: 50% lethal concentration. The values presented are the mean of three replicates (n =3) ± SD. SP: The specificity index calculated as the ratio of IC50 promastigotes/IC50 amastigotes. AmpB: amphotericin B.
