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. 2024 Mar 28;16(4):472. doi: 10.3390/pharmaceutics16040472

Table 1.

Extrusion parameters and temperatures for hot melt extrusion (S: solid plasticizer; L: liquid plasticizer).

Formulation Feed Rate (GF) [kg/h] Feed Rate (SP) [kg/h] Zone 1 [°C] Zone 2 [°C] Zone 3 [°C] Zone 4 [°C] Zone 5 [°C] Zone 6 [°C] Zone 7 [°C] Die [°C]
PVA 4-88 (S) 0.2 - 80 150 200 200 200 200 200 210
PVA 4-88 (L) 0.18 0.02 80 150 200 200 200 200 200 210
PVA 3-82 (S) 0.2 - 80 150 190 190 190 190 190 190
PVA 3-82 (L) 0.18 0.02 80 150 190 190 190 190 190 190