Table 1.
Summary of Studies Demonstrating Exercise Training Effects on the Composition of the Microbiome
| Model | Exercise Training | Effects of Exercise | Ref. # |
|---|---|---|---|
| Human: 32 previously sedentary women (n = 20) and men (n = 12) based on a lean or obese body mass index | 2 wk of baseline testing + 6 wk endurance-based exercise intervention + 6-wk washout period | Butyrate producers (Clostridiales spp., Lachnospira spp., Roseburia spp. f_Lachnospiraceae unclass, and Faecalibacterium spp.) increased. | 196 |
| Human: sedentary overweight women (n = 19) aged 36.8 ± 3.9 y | 6 wk of endurance training (40-60 min) | Dorea, Anaerofilum, and Akkermansia increased while unidentified Porphyromonadaceae, Odoribacter, unidentified Desulfovibrionaceae, and unidentified Enterobacteriaceae decreased. | 197 |
| Rat: male Sprague Dawley rats (5 wk old) | 6 d running wheels | Bifidobacterium and Lactobacillus increased; Bacteroides, Prevotella, Enteroccocus, and Clostridium decreased. | 198 |
| Mouse: male type 2 diabetic db/db mice (6 wk old) | 6 wk of low-intensity treadmill running (5 d/wk) | Bifidobacterium spp. and Methanobrevibacter spp. decreased; Lactobacillus spp. and Clostridium leptum increased. | 199 |
| Mouse: 8-wek-old male mice fed with HFD | 6 wk of treadmill running (1 h each day; 17-22 m/min) | Lactococcus was decreased 1 h after acute exercise, but change did not persist 1 wk after acute exercise. | 200 |
| Mouse: male C57BL/6 mice post-MI (8-10 wk old) | 8 wk of treadmill running (15 m/min) | Alistipes, Ruminococcus, Allobaculum, and Oscillospiraceae UCG-005 increased; Lachnospiraceae_UCG-001 decreased. | 165 |
HFD = high-fat diet; MI = myocardial infarction.