Disease progression in patients infected with New World hantaviruses, Nipah virus, or MERS-CoV. The different stages of disease are indicated, along with incubation time and minimum time from disease onset to death. Factors that are known to influence outcome of disease are also indicated. Abbreviations: ARDS, acute respiratory distress syndrome; HPS, hantavirus pulmonary syndrome; MERS, Middle East respiratory syndrome; MERS-CoV, Middle East respiratory syndrome coronavirus; MOD, multiorgan dysfunction.