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. 1998 Dec;72(12):10148–10156. doi: 10.1128/jvi.72.12.10148-10156.1998

TABLE 2.

Infectivity of SNV-derived vector particles displaying anti-CD34 scAs on various human cell lines

Source of vector particlesa Virus titer (CFU/ml)
KG1a Daudi HeLa D17
DSH-cxl <10 <10 <10   2 × 106
DSgp13-cxl-RD160 3 × 103 2 × 103 3 × 102 <10  
DSH-cxl-RD160 2 × 105 2 × 105   104   106
DSgp13-cxl-MLV-Env 2 × 102 5 × 102   105   105
a

All particles transduce a retroviral vector for expression of the bacterial β-galactosidase gene. DSH-cxl virus particles contain the wild-type SNV envelope; DSgp13-cxl-RD160 particles display chimeric anti-CD34 scA–SNV-Env fusion proteins; DSH-cxl-RD160 particles are similar to DSgp13-cxl-RD160 but also contain the SNV wild-type Env. DSgp13-cxl-MLV-Env particles contain SNV Gag-Pol proteins pseudotyped with ampho-MLV Env.