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. Author manuscript; available in PMC: 2024 Oct 4.
Published in final edited form as: Nat Microbiol. 2024 Jan 4;9(1):55–69. doi: 10.1038/s41564-023-01560-2

Extended Data Figure 10. Presence of irdA predicts itaconate reductase activity of E. lenta strains.

Extended Data Figure 10.

(A) Schematic diagram of itaconate reduction by IrdA, and sequence identity of the reductase with greatest similarity to IrdA is shown for indicated E. lenta strains strain. (B) Extracted ion chromatograms of authentic standard-matched methylsuccinate peaks from media collected after cultivation with the indicated strain.