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. 2024 Apr 27;36(1):100. doi: 10.1007/s40520-024-02733-7

Table 3.

Pre-post differences within groups reported for iTUG total duration

Author (Year) Compared groups/conditions Pre-intervention: mean total iTUG duration (sec; ± SD) Post-intervention: mean total iTUG duration post (sec; ± SD)
Patients with idiopathic normal pressure hydrocephalus (PwiNPH) – surgical and invasive procedures
 Ferrari (2020)a,c Before tap-test 24 h after tap-test 72 h after tap-test
Tap-test “pure” (p-iNPH) (n = 45) 17 (median) 16 (median) 15 (median)
Tap-test “secondary” (s-NPH) (n = 20) 22 (median) 20 (median) 18.5 (median)
 Ferrari (2022)c Tap-test and ventriculoperitoneal shunt surgery (n = 42)

Before tap-test

24.1 ± 15.7

72 h after tap-test

19.5 ± 8.1

6 months after shunt

16.4 ± 5.5**

 Yamada (2019)a Before tap-test 24 h after tap-test 96 h after tap-test
Tap-test positive (n = 28) 23.8 ± 15.8 18.3 ± 10.2 15.1 ± 7.7
Tap-test negative (n = 8) 16.4 ± 6.8 18.0 ± 10.0 16.4 ± 7.6
Ventriculoperitoneal shunt surgery (n = 18, of those who were diagnosed tap-test-positive) 17.4 ± 5.0

After shunt

11.8 ± 3.1

 Ishikawa (2019) Before tap-test N/A (no data for iTUG total duration changes available, data for single iTUG segments: see Table 4)
IG: tap-test/ventriculoperitoneal shunt surgery (n = 32) 19.4 ± 9.4
CG: activity program (n = 87) 12.5 ± 4.1
Patients with Parkinson’s disease (PwPD)—pharmacological intervention
 Dibilio (2017) Medication off vs. on (n = 28) Off: 20.2 ± 12.6 On: 15.4 ± 5.2*
 Miller Koop (2018) Medication off vs. on (n = 20) Off: 8.2 ± 2.3 (median ± interquartile Range) On: 7.4 ± 1.9* (median ± interquartile range)
Orthopedic conditions—elective surgery
 Bloomfield (2019) Before surgery Baseline vs. 2w after surgery Baseline vs. 6w after surgery Baseline vs. 12w after surgery
Total knee replacement, moderate function (n = 46) 12.6 ± 2.4 21.8b,** 13b 11.7b
Total knee replacement, low function (n = 22) 21.6 ± 5.7 29.2b 18.7b 16.7b,**
 Perelgut (2020) Before surgery 2w after surgery 52w after surgery
Total hip replacement, collared stem (n = 23) 13.0 ± 4.2c 16.3b 11.2b,**
Total hip replacement, collarless stem (n = 26) 13.4 ± 3.1c 15.6b 10.9b,**
Exercise and rehabilitation interventions in different settings and populations
 Patients with Parkinson’s disease (PwPD)
  Flood (2020)c Before intervention 2w after intervention 8w after intervention 13w after intervention
IG: PwPD, LSVT-BIG® therapy (n = 12) 9.4 7.7 7.7 7.5**
CG1: PwPD, no therapy (n = 8) 11.9 N/A (CG1 and CG2 were only measured at baseline)
CG2: healthy controls (n = 14) 8.5
  Mollinedo-Cardalda (2018) Before intervention End of intervention 4 weeks after intervention
IG: PwPD, mat pilates program (n = 12) 9.4 ± 2.4 7.8 ± 2.8** 7.8 ± 5.6
CG: PwPD, calisthenics exercises (n = 10) 9.1 ± 2.7 9.2 ± 2.5 9.6 ± 1.4
  Picardi (2020) PwPD, inpatient rehabilitation (physiotherapy, occupational therapy) (n = 20)

Beginning of inpatient stay

15.8 ± 4.3

End of inpatient stay

14.1 ± 4.2*

 Participants recruited in outpatient settings
  Smith (2021) Older people, “Better Bones” exercise program (n = 54)

Before intervention

6.3 ± 1.4

After intervention

5.8 ± 1.1**

  Celletti (2020) Low back pain, back school (n = 44)

Before intervention

13.4 ± 3.9

After intervention

11.3 ± 2.2**

  Doheny (2013) Healthy sedentary, step exercise (n = 33)

9.2 ± 1.2 (T1 = baseline);

8.8 ± 11.1 (T2 = 4w after T1, before start of intervention)

After intervention (T3)

8.9 ± 1.3

  Williams (2021) IG: dementia, Tai Chi (n = 33) N/A (no data for iTUG total duration changes available, data for single iTUG segments available, see Table 4)
CG: dementia, usual care (n = 34)
Participants recruited in inpatient and institutionalized settings
  Caronni (2019) Peripheral neuropathy lower limbs, inpatient physiotherapy/occupational therapy rehabilitation (n = 25)

Before rehabilitation

18.7 ± 7.8

End of rehabilitation

15.1 ± 5.2**

  Cancela Carral (2017) 80 + years Before intervention 1w after intervention
Aerobic exercise (n = 13) 30.3 ± 21.4 26.6 ± 20.3
Muscle resistance exercise (n = 12) 29.1 ± 5.4 24.2 ± 8.4
Joint mobility exercise (n = 11) 30.3 ± 11.9 33.2 ± 13.6
  Cancela Carral (2019) 85 + years Before intervention Last week of intervention
Strength program (n = 11) 28.1 ± 10.0 27.7 ± 11.6
Control group (n = 13) 35.1 ± 11.6 38.6 ± 15.4*
Assistive devices
  Toosizadeh (2020)a Older people No calf vibration 30 Hz 40 Hz
Vibratory stimulation, moderate function (n = 10) 11.3 ± 2.8 12.5b 12.9b
Vibratory stimulation, low function (n = 10): 24.0 ± 10.0 23.3b 23.5b
  Yalla (2014) Older people, ankle foot orthosis (n = 30)

Shoe alone

13.8 ± 0.6

Shoe + ankle foot orthosis

14.1 ± 0.7

IG intervention group, N/A data not available, p-iNPH idiopathic normal pressure hydrocephalus with pure hydrocephalus, s-NPH secondary normal pressure hydrocephalus, LSVT-BIG® Lee Silverman Voice Treatment, w weeks

*p < 0.05, ** p < 0.01 compared to baseline

asignificance of pre-post differences not reported

bCalculated by the authors of this review

cInformation received on request from the authors of the respective article, CG = control group