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. 2024 Mar 22;29(5-6):785–798. doi: 10.1007/s10495-024-01950-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The efects of LIPUS and TRPV4 in mouse articular cartilage. A Calcium; B Calcium; C Expression of COL II; D Expression of ACAN; E Expression of BIP; F TUNEL; *p < 0.05 compared to N; ^#p < 0.05 compared to OA, (n = 3). N normal chondrocyte, NU norma + Low intensity pulsed ultrasound chondrocyte, OA osteoarthritis chondrocyte, OAU osteoarthritis + Low intensity pulsed ultrasound chondrocyte, NT- normal + GSK219 chondrocyte, OAT- osteoarthritis + GSK219 chondrocyte, N sham, OA osteoarthritis, UT- Low intensity pulsed ultrasound + GSK219, UT + Low intensity pulsed ultrasound + GSK101