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(A) Kaplan–Meier estimates of OS and intermediate clinical endpoints (ICEs). (B) Estimated hazard across times for OS and intermediate clinical endpoints (ICEs). OS, overall survival; DFS, disease-free survival; DDFS, distant disease-free survival; RFS, recurrence-free survival; DRFS, distant relapse-free survival; IBCFS, invasive breast cancer–free survival; RFI, recurrence-free interval; DRFI, distant recurrence-free interval; BCFI, breast cancer-free interval.
