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. 2018 Sep;366(3):479–484. doi: 10.1124/jpet.118.249938

TABLE 3.

LPV concentration (nanograms per milliliter) in MP, BM, and IP over 6 months postpartum

Values are presented as the median (IQR) of individual ratios, n (the number of samples available for analysis, of a possible 32 samples; missing samples due to shipping error), unless otherwise noted.

Study Visit
MPa
BMb
IPc
BM/MP Ratio
IP/MP Ratiod
Relative Infant Dose
%
Month 1 1870 (586–4190) n = 4 530 (150–890) n = 6 < LOQ n = 3 0.39 (0.07–0.62)
Month 3 10,900 (5495–15,750) n = 9 650 (160–940) n = 8 < LOQ n = 9 0.056 (0.036–0.064)
Month 6 5790 (1230–10,600) n = 8 590 (200–770) n = 8 < LOQ n = 8 0.088 (0.06–0.14) 0.23
a

MP LPV was below the LOQ in one sample in months 1 and 6.

b

BM LPV was below the LOQ in one sample in months 1 and 3, and in two samples in month 6.

c

IP LPV was below the LOQ in three, eight, and seven samples in months 1, 3, and 6, respectively.

d

LPV concentration fell below the LOQ for all IP samples; therefore, the IP/MP ratio was not calculated.