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. 2024 Mar 5;18:193–208. doi: 10.1016/j.xjon.2024.02.018

Table 2.

Operative data by treatment group

Variables RIPC (n = 60) Control (n = 60)
Anesthesia
 Volatile anesthetic agent: isoflurane 56 (93%) 55 (92%)
 Volatile anesthetic agent: sevoflurane 4 (7%) 5 (8%)
 MAC volatile anesthetic pre-CPB, % 0.7 [0.6-0.9] 0.8 [0.7-1.0]
Time from start of intervention to aortic XC, min 93 [81-105] 92 [77-103]
In TOF repair (n = 34) (n = 34)
 RVOT muscle resected 34 (100%) 33 (97%)
 RVOT stent removed 6 (86%) 7 (100%)
 RVOT/TA/PA patch used 32 (94%) 33 (97%)
 RV-PA conduit used 2 (6%) 1 (3%)
In isolated VSD closure (n = 26) (n = 26)
 RVOT muscle resected 5 (19%) 3 (12%)
VSD closed 60 (100%) 59 (98%)
Total CPB time, min 91.0 [67.0-114.0] 87.5 [70.0-106.5]
Repeat CPB required 7 (12%) 5 (8%)
Total aortic XC time, min 64.0 [45.0-84.5] 58.5 [44.5-74.0]
Repeat aortic XC required 6 (10%) 5 (8%)
Type of cardioplegia used
 Cold blood 54 (90%) 53 (88%)
 Cold crystalloid 6 (10%) 6 (10%)
 Warm blood 0 1 (2%)
No. of cardioplegia doses 2 [2-3] 2 [2-3]
Total cardioplegia volume, mL 360 [272-450] 369 [294-450]
Postoperative recovery
 Drain loss at 12 h, mL 55.0 [45.0-87.5] 79.5 [40.0-107.5]
 Blood transfusion post-CPB in first 12 h 13 (22%) 11 (18%)
 Volume blood transfused in first 12 h, mL/kg in those transfused 75 [55-100] 50 [30-80]
 Hemoglobin at 12 h, g/dL 119 [111-134] 119 [107-130]
 Time to extubation, h 6.3 [3.7-15.2] 6.9 [3.6-13.3]

Data are median [IQR] when appropriate. RIPC, Remote ischemic preconditioning; MAC, minimum alveolar concentration; CPB, cardiopulmonary bypass; XC, crossclamp; TOF, tetralogy of Fallot; RVOT, right ventricular outflow tract; TA, transannular; PA, pulmonary artery; RV-PA, right ventricle to pulmonary artery; VSD, ventricular septal defect.

Of the 7 participants in each treatment arm with TOF and an RVOT stent.

Small infant with TOF and bilateral superior vena cavae in whom an RV-PA conduit was placed but complete repair was abandoned.