Table E4.
Cardiac index in the first 12 hours measured using ICON in Birmingham only
| Cardiac index (L/min/m2) | RIPC mean (SD, n) | Control mean (SD, n) | Point estimate (95% CI), P value∗ |
|---|---|---|---|
| Baseline | 3.7 (1.3, 41) | 4.1 (1.3, 41) | (–0.16 to 0.59), .22 |
| 3 h | 3.8 (1.4, 36) | 3.7 (1.1, 38) | |
| 6 h | 3.7 (1.3, 39) | 3.8 (1.4, 37) | |
| 9 h | 3.6 (1.0, 37) | 3.8 (1.4, 32) | |
| 12 h | 3.6 (1.0, 35) | 3.8 (1.5, 29) |
RIPC, Remote ischemic preconditioning; SD, standard deviation; CI, confidence interval.
∗
Average mean difference over each time point (RIPC – Control) calculated using a mixed linear regression model adjusting for baseline value. A positive difference favors the RIPC group.