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. 2024 Apr 15;15:1373371. doi: 10.3389/fimmu.2024.1373371

Table 3.

Univariate and multivariate Cox regression models of CAR with mortality in patients with AP.

Outcome Unadjusted, HR (95%CI) Model 1, HR (95%CI) Model 2, HR (95%CI)
7-d
 CAR<0.446 1 1 1
 CAR≥0.446 3.98 (1.40-11.28) 3.82 (1.33-10.94) 3.63 (1.19-11.04)
P for trend 0.010 0.013 0.023
14-d
 CAR<0.446 1 1 1
 CAR≥0.446 3.40 (1.70-6.80) 2.99 (1.48-6.04) 3.11 (1.52-6.36)
P for trend 0.001 0.002 0.002
21-d
 CAR<0.446 1 1 1
 CAR≥0.446 3.68 (1.99-6.79) 3.11 (1.67-5.81) 3.34 (1.77-6.30)
P for trend <0.001 <0.001 <0.001
28-d
 CAR<0.446 1 1 1
 CAR≥0.446 3.91 (2.17-7.05) 3.39 (1.86-6.16) 3.58 (1.95-6.59)
P for trend <0.001 <0.001 <0.001
90-d
 CAR<0.446 1 1 1
 CAR≥0.446 3.04 (1.97-4.68) 2.67 (1.72-4.15) 2.77 (1.77-4.34)
P for trend <0.001 <0.001 <0.001
1-year
 CAR<0.446 1 1 1
 CAR≥0.446 2.70 (1.85-3.93) 2.33 (1.59-3.43) 2.39 (1.61-3.54)
P for trend <0.001 <0.001 <0.001

Model 1: Adjusted age and gender.

Model 2: Model 1+ Spo2+Temperature+Vasopressin+Betablockers+Plt+HCT.