Comparison of ROI intensity on T2W MRI scans obtained from Walker-256 carcinosarcoma-bearing rats, median (min; max).
| Group | Tumor, a.u. | Muscle, a.u. | Background, a.u. | Tumor/muscle ratio | Tumor contrast |
|---|---|---|---|---|---|
| Control | 794.6 (519.4; 2476.7) | 1268.4 (130.7; 3997.1) | 36.1 (0; 141.0) | 0.6 | 21.0 |
| DOX | 693.4a (285.6; 1358.0) | 706.0a (150.9; 2518.5) | 41.3a (0; 111.4) | 1.0 | 15.8 |
| DOX-MNC | 609.1a,b (217.3; 1333.9) | 317.0a,b (37.4; 2368.7) | 26.7a,b (0; 119.3) | 1.9 | 21.8 |
| DOX-MNC + CMF + EMF | 1110.3a,b,c (429.0; 1769.5) | 805.6a,b,c (154.7; 3945.8) | 42.4a,b,c (0; 112.3) | 1.4 | 25.2 |
a
Significant difference from control, p < 0.05.
b
Significant difference from DOX, p < 0.05.
c
Significant difference from DOX-MNC, p < 0.05.