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. Author manuscript; available in PMC: 2024 Apr 29.
Published in final edited form as: Fertil Steril. 2015 Apr 14;103(6):1537–1543. doi: 10.1016/j.fertnstert.2015.03.003

TABLE 1.

Cycle characteristic by infertility diagnosis, all fresh nondonor IVF cycles 2000–2011.

Primary diagnosis
Endometriosis Male factor
Characteristic n % n % P value
Total 112,475 375,557
Age (y) < .0001
 <35 56,156 49.9 180,322 48.0
 35–37 27,330 24.3 83,319 22.2
 38–40 20,037 17.8 70,508 18.8
 41–42 6,441 5.7 27,600 7.4
 43–44 2,092 1.9 10,878 2.9
 ≥45 419 0.4 2,930 0.8
Race/ethnicitya < .0001
 Non-Hispanic white 54,288 80.4 171,507 76.0
 Non-Hispanic black 2,642 3.9 13,657 6.1
 Asian/Pacific islander 6,142 9.1 22,199 9.8
 Hispanic 4,414 6.5 17,880 7.9
 Other 84 0.1 391 0.2
Concomitant diagnosis
 Ovulatory dysfunction 9,951 8.9 47,387 12.6 < .0001
 Tubal factor 21,198 18.9 37,391 10.0 < .0001
 Diminished ovarian reserve 14,863 13.2 61,618 16.4 < .0001
No. of prior ART cycles .0077
 0 62,221 55.4 209,571 55.8
 1 23,356 20.8 76,625 20.4
 2+ 26,820 23.9 89,091 23.7
No. of prior pregnancies < .0001
 0 59,921 53.3 198,509 52.9
 1 30,747 27.4 98,867 26.4
 2+ 21,701 19.3 77,575 20.7
No. of prior spontaneous abortions < .0001
 0 80,761 72.0 281,045 75.2
 1 21,866 19.5 65,906 17.6
 2+ 9,573 8.5 27,000 7.2
No. of prior preterm births < .0001
 0 110,110 98.2 366,005 98.0
 1 1,873 1.7 6,608 1.8
 2+ 159 0.1 737 0.2
No. of prior full-term births < .0001
 0 88,712 79.0 284,526 76.0
 1 20,678 18.4 71,211 19.0
 2+ 2,862 2.6 18,594 5.0
Mean maximum serum FSH (SD)a 7.98 4.9 7.54 4.4 < .0001
Cycle history < .0001
 First IVF, no previous live birth 52,453 46.8 171,171 45.7
 First IVF, ≥1 previous live birth 9,653 8.6 37,668 10.1
 ≥1 previous IVF, no previous live birth 34,627 30.9 107,960 28.9
 ≥1 previous IVF, ≥1 previous live birth 15,462 13.8 57,413 15.3
Stimulation protocol (only 2004+ data)a < .0001
 Agonist standard 34,515 48.7 132,966 49.7
 Agonist flare 9,057 12.8 29,472 11.0
 Antagonist 21,788 30.7 84,912 31.7
 Clomid ± FSH 1,015 1.4 3,336 1.3
 FSH only 2,160 3.0 7,856 2.9
 Unstimulated 611 0.9 2,759 1.0
 Other 1,797 2.5 6,489 2.4
Mean total FSH dose (SD)a 3,274.32 1,732.2 3,106.54 1,672.1 < .0001
Ovarian hyperstimulation < .0001
 Yes 1,187 1.1 4,929 1.3
 No 111,287 98.9 370,625 98.7
Cycle cancellation total < .0001
 Before retrieval 14,474 12.9 37,936 10.1
 Between retrieval and transfer 6,281 5.6 23,084 6.2
 Not cancelled 91,720 81.6 314,537 83.8
Hospitalization 337 0.3 1,175 0.3 .4832
a

All missing <1% except race/ethnicity (39.9%), maximum serum FSH (25.5%), and mean FSH dose (3.7%).