Table 2. Intervention effects on primary and secondary outcomes. [CI=confidence interval; HRR=heart rate reserve; IIr=isometric log-ratio; SD=standard deviation.].

Variable		Time		Intervention group			Control group			Estimated treatment effect		P-value
				N	Mean (SD)		N	Mean (SD)		Mean	95% CI
Primary outcome
	Heart rate (hours/day)
		<60% HRR	Baseline	31	6.08 (0.89)		38	6.49 (1.10)
			Follow-up	31	6.17 (1.02)		38	6.31 (0.85)
		≥60% HRR	Baseline	31	0.08 (0.15)		38	0.02 (0.04)
			Follow-up	31	0.07 (0.13)		38	0.03 (0.05)
Ilr1 ≥60% HRR vs. <60% HRR										-0.36	-1.10–0.37	0.34
Secondary outcomes
	HR during sleep (beats/minute)
			Baseline	33	48.2 (7.2)		44	48.0 (6.2)
			Follow-up	33	47.6 (8.3)		44	47.9 (6.8)		0.51	-1.51–2.55	0.63
	Physical behaviors (hours/day)
		Non active	Baseline	42	5.37 (0.75)		56	5.70 (0.65)
			Follow-up	42	5.41 (0.84)		56	5.54 (0.63)
		Active	Baseline	42	1.11 (0.30)		56	1.23 (0.36)
			Follow-up	42	1.20 (0.31)		56	1.28 (0.38)
Ilr2, active vs. non active										0.01	-0.05–0.06	0.25
	Pain (0–10)
			Baseline	45	3.7 (3.0)		58	2.7 (2.3)
			Follow-up	45	3.6 (2.9)		58	3.0 (2.3)		-0.28	-1.02–0.46	0.47
	Physical exhaustion (0–10)
			Baseline	46	3.9 (2.3)		58	4.1 (2.0)
			Follow-up	46	3.5 (2.4)		58	3.9 (2.2)		-0.17	-0.97–0.65	0.69
	Energy at work (0–10)
			Baseline	46	6.9 (1.7)		58	7.5 (1.3)
			Follow-up	46	7.4 (1.6)		58	7.2 (1.5)		0.65	0.08–1.21	0.03
	Need for recovery (1–5)
			Baseline	44	3.3 (0.8)		58	3.1 (0.7)
			Follow-up	44	3.2 (0.9)		58	3.3 (0.8)		-0.32	-0.54– -0.09	0.01
	Work productivity (0–10)
			Baseline	45	7.3 (1.5)		58	7.3 (1.4)
			Follow-up	45	7.7 (1.3)		58	7.3 (1.3)		0.27	-0.31–0.85	0.36