Table 2.

Plasma SPM, SPM pathway intermediates and LTB4 in men and women.

	Men	Women	P value for sex difference
AA derived metabolites (pg/ml)
LTB4	10.4 (6.7,16.0) (n = 28)	8.9 (6.0, 13.2) (n = 31)	0.60
LXA4	14.5 (11.1, 19.0) (n = 38)	9.0 (5.7, 14.2) (n = 22)	0.05
EPA derived metabolites and E-series resolvins (pg/ml)
18-HEPE	45.0 (40.6, 49.8) (n = 477)	45.1 (44.0, 49.8) (n = 498)	0.97
RvE1	6.5 (6.0, 7.1) (n = 297)	5.2 (4.9, 5.5) (n = 337)	<0.0001
RvE2	10.7 (6.5, 16.2) (n = 23)	11.4 (8.3, 15.7) (n = 23)	0.68
RvE3	19.2 (16.4, 22.3) (n = 259)	15.9 (13.8, 18.5) (n = 281)	0.09
DHA derived metabolites and D-series resolvins (pg/ml)
17-HDHA	123.7 (111.9, 136.9) (n = 479)	130.1 (117.4, 144.3) (n = 499)	0.01
RvD1	7.4 (4.2, 13.1) (n = 18)	8.7 (5.3, 14.4) (n = 27)	0.66
17R-RvD1	9.6 (7.7, 12.1) (n = 68)	6.4 (4.5, 9.2) (n = 48)	0.05
RvD2	6.4 (4.5, 9.0) (n = 40)	6.6 (4.0, 11.0) (n = 28)	0.91
RvD3	5.2 (4.2,4.6) (n = 21)	5.1 (4.1,6.3) (n = 21)	0.90
RvD5	2.9 (1.7, 5.1) (n = 25)	4.3 (3.0, 6.2) (n = 24)	0.25
10S,17S-HDHA	10.4 (7.0, 15.3) (n = 70)	12.0 (8.6, 16.7) (n = 80)	0.55
PD1	32.5 (20.1, 52.4) (n = 52)	48.6 (34.0, 69.3) (n = 58)	0.17
DHA derived metabolites and maresins (pg/ml)
14-HDHA	123.7(111.9, 136.9) (n = 479)	130.1 (117.4, 144.3) (n = 499)	0.50
MaR1	11.7 (8.8, 15.7) (n = 49)	10.5 (8.2, 13.4) (n = 51)	0.55

Values are geometric mean and 95% CI.

Bold values indicate significant differences between sexes.