Table 2. Multivariable Cox Proportional Hazards Model for Association of Screen Detection With Overall Survival, Adjusting for Lead-Time Bias.

Variable	HR (95% CI)a
Crude (unadjusted)
Non–screen-detected hepatocellular carcinoma	1 [Reference]
Screen-detected hepatocellular carcinoma	0.65 (0.56-0.75)
Adjusted for lead-time bias
Mean sojourn time of 4 mo	0.74 (0.64-0.85)
Mean sojourn time of 5 mo	0.75 (0.65-0.87)
Mean sojourn time of 6 mo	0.77 (0.67-0.89)

Abbreviation: HR, hazard ratio.

^a Adjusted for age at diagnosis, sex, race, body mass index, insurance status, liver disease etiology, Child Pugh class as a continuous variable, and Eastern Cooperative Oncology Group class.