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. Author manuscript; available in PMC: 2024 Apr 30.
Published in final edited form as: J Am Chem Soc. 2023 Nov 9;145(46):25318–25331. doi: 10.1021/jacs.3c08940

Figure 1.

Figure 1.

sEH protein and its inhibitors: (A) 2D representation of sEH inhibitors; (B) the combined epoxide-phosphatase domain: the binding region is highlighted in red; (C) the Ligand2 bound sEH protein with the two most interacting residues in the bound state.