TABLE 3.
Differences in a Composite Late Effects and Death Outcomes by Off-Trial and On-Trial Group Matched Pairs
| Standard Therapy Off Trial | |||||
|---|---|---|---|---|---|
|
|
|||||
| 0 to 1 Systems Affected | 2 to 5 Systems Affected | Deaths | Total | ||
| On Trial | 0–1 systems affected | 91 | 28 | 26 | 145 |
| 2–5 systems affected | 19 | 11 | 7 | 37 | |
| Deaths | 18 | 4 | 10 | 32 | |
| Total | 128 | 43 | 43 | 214 | |
Late effects and death were categorized as: 1) 0 to 1 organ systems; 2) greater than or equal to 2 organ systems; and 3) death. The relative odds that the on-therapy group had lower (better) morbidity-mortality scores compared with the standard therapy group was 1.46 (95% confidence interval, 0.97–2.20; P = .070).