Table 1.
Baseline characteristics according to quartiles of the TyG index
| Variables | Total (n = 64,489) |
Quartile 1 (n = 16,121) |
Quartile 2 (n = 16,122) |
Quartile 3 (n = 16,124) |
Quartile 4 (n = 16,122) |
P value |
|---|---|---|---|---|---|---|
| Age, years | 44.9 ± 8.9 | 43.2 ± 9.5 | 44.7 ± 8.9 | 45.6 ± 8.6 | 46.3 ± 8.1 | < 0.0001 |
| Male, n (%) | 46,479 (72.07) | 10,092 (62.60)) | 11,445 (70.99) | 12,048 (74.72) | 12,894 (79.98) | < 0.0001 |
| BMI, kg/m2 | 25.04 ± 3.49 | 23.35 ± 3.18 | 24.63 ± 3.27 | 25.65 ± 3.32 | 26.52 ± 3.35 | < 0.0001 |
| SBP, mmHg | 126.79 ± 19.34 | 119.83 ± 17.46 | 125.34 ± 18.40 | 128.70 ± 19.13 | 133.28 ± 19.76 | < 0.0001 |
| DBP, mmHg | 82.70 ± 11.76 | 78.37 ± 10.71 | 81.95 ± 11.30 | 83.92 ± 11.50 | 86.55 ± 11.97 | < 0.0001 |
| TyG index | 8.65 ± 0.70 | 7.83 ± 0.27 | 8.38 ± 0.11 | 8.80 ± 0.14 | 9.60 ± 0.47 | < 0.0001 |
| FBG, mmol/L | 5.41 ± 1.55 | 4.83 ± 0.65 | 5.07 ± 0.72 | 5.39 ± 1.03 | 6.36 ± 2.51 | < 0.0001 |
| TC, mmol/L | 4.93 ± 1.10 | 4.63 ± 0.87 | 4.89 ± 0.92 | 5.11 ± 0.98 | 5.10 ± 1.44 | < 0.0001 |
| TG, mmol/L | 1.27 (0.89–1.96) | 0.69 (0.57–0.80) | 1.09 (0.98–1.21) | 1.56 (1.37–1.79) | 2.87 (2.27–4.05) | < 0.0001 |
| HDL-C, mmol/L | 1.53 ± 0.37 | 1.54 ± 0.38 | 1.54 ± 0.36 | 1.52 ± 0.36 | 1.52 ± 0.40 | < 0.0001 |
| LDL-C, mmol/L | 2.36 ± 0.83 | 2.20 ± 0.85 | 2.39 ± 0.77 | 2.47 ± 0.79 | 2.37 ± 0.89 | < 0.0001 |
| hs-CRP, mg/L | 0.70 (0.27–1.90) | 0.50 (0.20–1.53) | 0.64 (0.24–1.70) | 0.77 (0.30–1.90) | 0.93 (0.36–2.33) | < 0.0001 |
| Hypertension, n (%) | 23,384 (36.26) | 3275 (20.32) | 5296 (32.85) | 6610 (40.99) | 8203 (50.88) | < 0.0001 |
| Diabetes mellitus, n (%) | 4722 (7.32) | 122 (0.76) | 281 (1.74) | 914 (5.67) | 3405 (21.12) | < 0.0001 |
| Smoking, n (%) | 22,728 (35.24) | 5213 (32.34) | 5198 (32.24) | 5771 (35.79) | 6546 (40.60) | < 0.0001 |
| Drinking, n (%) | 25,038 (38.83) | 6052 (37.54) | 5715 (35.45) | 6242 (38.71) | 7029 (43.60) | < 0.0001 |
| Snoring, n (%) | 22,571 (35.00) | 5348 (33.17) | 5146 (31.92) | 5723 (35.49) | 6354 (39.41) | < 0.0001 |
| High educational background, n (%) | 15,318 (23.75) | 4878 (30.26) | 3625 (22.48) | 3611 (22.40) | 3204 (19.87) | < 0.0001 |
| Antihypertensive agents, n (%) | 4707 (7.30) | 629 (3.90) | 854 (5.30) | 1384 (8.58) | 1840 (11.41) | < 0.0001 |
| Antidiabetic agents, n (%) | 915 (1.42) | 46 (0.29) | 83 (0.51) | 192 (1.19) | 594 (3.68) | < 0.0001 |
| Lipid-lowering agents, n (%) | 381 (0.59) | 35 (0.22) | 66 (0.41) | 90 (0.56) | 190 (1.18) | < 0.0001 |
BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TyG index triglyceride-glucose index, FBG fasting blood glucose, TC total cholesterol, TG triglyceride, HDL-C high density lipoproteincholesterol, LDL-C low density lipoproteincholesterol, hs-CRP high sensitivity C-reactive protein