Table 5.

Incremental predictive value of the TyG index for ASCVD events and all-cause mortality

	C-statistic (95% CI)	P-value	Category-free NRI (95% CI)	P-value	IDI (95% CI)	P-value
ASCVD events
Clinical risk factors	0.7866 (0.7773–0.7960)		–	–	–	–
Clinical risk factors + TG	0.7870 (0.7776–0.7963)	< 0.001	0.1021 (0.0588–0.1454)	< 0.001	< 0.0001 (0–0.0010)	0.3513
Clinical risk factors + FBG	0.7877 (0.7783–0.7970)	< 0.001	0.0455 (0.0009–0.0902)	0.0459	0.0003 (0–0.0.0006)	0.0198
Clinical risk factors + TyG index	0.7883 (0.7790–0.7976)	< 0.001	0.1607 (0.1160–0.2054)	< 0.001	0.0004 (0.0002–0.0006)	0.0003
All-cause mortality
Clinical risk factors	0.7132 (0.7004–0.7260)		–	–	–	–
Clinical risk factors + TG	0.7135 (0.7007–0.7263)	< 0.001	0.0784 (0.0275–0.1293)	0.0038	< 0.0001 (0–0.0001)	0.0890
Clinical risk factors + FBG	0.7138 (0.7011–0.7266)	< 0.001	− 0.0309 ( − 0.0837–0.0218)	0.2536	0.0010 (0.0005–0.0015)	< 0.001
Clinical risk factors + TyG index	0.7143 (0.7015–0.7271)	< 0.001	0.1235 (0.0705–0.1766)	< 0.001	0.0003 (0.0002–0.0005)	< 0.001

ASCVD atherosclerotic cardiovascular disease, TG triglyceride, FBG fasting bloodglucose, TyG index triglyceride-glucose index, BMI body mass index, SBP systolic blood pressure, CVD cardiovascular disease, TC total cholesterol, HDL-C high density lipoproteincholesterol, LDL-C low density lipoproteincholesterol, hs-CRP high sensitivity C-reactive protein