Fig. 3.

Effect of estrous cycle on incubation of craving after long-access and intermittent-access cocaine self-administration in female rats. Relapse (incubation) test. Mean ± S.E.M. number of active lever presses per session after continuous (nonestrus: n = 12 for day 2 and 29, estrus: n = 9/8 for day 2/29) and intermittent (nonestrus: n = 13/16 for day 2/29, estrus n = 10/7 for days 2/29) access drug self-administration. * Different from day 2 within each estrous phase, P < 0.05; # Different from nonestrus on day 29, P < 0.05. Adapted from Nicolas et al. (2019). Figure 3 was reproduced with permission from Elsevier.