An 2008.
Methods | Randomized controlled trial January 2006 to January 2007 |
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Participants | Patients with histologically confirmed colon cancer undergoing elective resection Participants randomized: 51 (27 CHO, 24 fasting) Participants analysed: 51 (27 CHO, 24 fasting) Exclusions: diabetes mellitus, medication use that might affect insulin sensitivity, renal or hepatic insufficiency, inflammation |
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Interventions | Carbohydrates: oral beverage containing 50 g of carbohydrates in 200 mL administered 3 hours before anaesthesia Fasting: nil by mouth for 6 hours for solids and 2 hours for liquids before surgery |
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Outcomes | Length of hospital stay, postop time to passage of flatus | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Details of sequence generation not reported |
Allocation concealment (selection bias) | Unclear risk | Details of allocation concealment not reported |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded; this may affect subjective outcomes |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Participants and personnel were not blinded; this may affect subjective outcomes |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No postrandomization withdrawals reported in this study |
Selective reporting (reporting bias) | Unclear risk | Trial protocol was not published, and not all important outcomes were reported |
Other bias | Low risk | No other important threats to validity have been identified in this study; however limited information is available in the text |