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. Author manuscript; available in PMC: 2025 May 1.
Published in final edited form as: Otolaryngol Head Neck Surg. 2024 Feb 28;170(5):1430–1441. doi: 10.1002/ohn.670

Table 5:

Mixed models analysis correlating proportion of infants with failed NBHS who underwent CMV testing to factors involved in early CMV screening:

Protocol characteristic (present vs. not) Odds Ratio (OR) (95% Confidence Interval) p-value

Nurse facilitates cCMV testing 5.9 (3.4, 10.2) < 0.001

PCP orders cCMV testing 5.4 (3.1, 9.2) <0.001

Conditional cCMV test order set 5.3 (3.2, 8.7) < 0.001

Provider contacting for cCMV+ test:
 Neonatologist 3.7 (2.2, 6.0) < 0.001
 Primary care 0.2 (0.1, 0.3) < 0.001
 Audiologist 2.9 (1.22, 6.75) 0.015
 Other 0.3 (0.2, 0.5) < 0.001

Diagnostic testing after cCMV+ test:
 Head US 20.8 (13.6, 31.5) < 0.001
 CMP 0.8 (0.6, 1.1) 0.14

Head ultrasound ordered if cCMV positive test result 20.8 (13.6, 31.5) < 0.001

A Multidisciplinary team involved in cCMV evaluation and treatment 18.7 (6.0, 58.3) < 0.001

Process to contact cCMV+ infants LTFU 8.4 (6.7, 10.6) < 0.001

Track cCMV+ patient symptoms 0.26 (0.13, 0.50) < 0.001

cCMV = congenital CMV; cCMV+ = positive congenital CMV test; Head US = head ultrasound; CMP = complete metabolic panel; LTFU = lost to follow-up