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Correlation of actin redistribution, palmitoylation, and enzymatic activities of NSP1 in HeLa cells expressing wild-type or mutant SFV or SIN NSP1 proteins
| Type of protein expressed | MT activity (11)a | GT activity (1)a | Palmitoyl-ationa | Stress fibers | Induction of filopodia |
|---|---|---|---|---|---|
| SFV NSP1 (wild type) | + | + | + | − | + |
| SFV C418-420A | + | + | − | + | − |
| SFV H38A | ++ | − | + | − | + |
| SFV D64A | − | − | + | − | + |
| SFV D90A | − | − | + | − | + |
| SFV Δ121-146 | − | − | − | + | − |
| SIN NSP1 (wild type) | + | + | + | − | + |
| SIN C420A | + | + | − | + | − |
