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Commonly observed mutations from evolved isolates
| Region | Product | Unique mutations | Frequency (n = 18, final populations and clones) | ALE lineages |
|---|---|---|---|---|
| fusA | Elongation factor G | D560N | 10 | ALE1, ALE3, ALE4, ALE6 |
| V531A | 2 | ALE5 | ||
| S309T | 1 | ALE5 | ||
| E549K | 2 | ALE3 | ||
| D560G | 3 | ALE2 | ||
| abrB | Transition state genes transcriptional regulator |
−46 T→A −51 CG→TC |
6 | ALE4, ALE6 |
| −62 G→A | 3 | ALE5 |
