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. 2024 Apr 30;15:3635. doi: 10.1038/s41467-024-47943-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Enrichment of differentially hydroxymethylated CpGs at specific genomic contexts by tumor type and direction of differential methylation as represented by odds ratios and 95% confidence intervals. Odds ratio points and confidence intervals colored by tumor type. The direction of 5hmC change is indicated by the shape indicating the odds ratio. Odds ratios were calculated by Mantel-Haenszel test. Source data are provided as a Source Data file.