Table 2.
Clinical Characteristics of patients with biopsy proven NAFLD.
| Variables (n = 147) | Mild to moderate fibrosis (n = 91) |
Advanced fibrosis (n = 56) | P value | Test |
|---|---|---|---|---|
| Age | 42.06 ± 11.86 | 55.08 ± 8.74 | <0.001 | t test |
| Sex | ||||
| Male (n = 84) Female (n = 63) |
48 (57%) 43 (68%) |
36 (43%) 20 (32%) |
0.16 | Chi-square test |
| BMI | 25.55 ± 3.61 | 27.04 ± 4.27 | 0.03 | t test |
| DM | ||||
| Yes (n = 48) No (n = 99) |
12 (25%) 79(79.8) |
36 (75%) 20 (20.2%) |
<0.001 | Chi-square test |
| Height (cm) | 161.4 ± 9.58 | 164.15 ± 8.31 | 0.06 | t test |
| Platelet | 264,253 ± 60,166 | 137,750 ± 78,886 | <0.001 | t test |
| AST | 23 (12, 82) | 50.5 (13, 182) | <0.001 | Mann–Whitney U Test |
| ALT | 25.2(10,88) | 30.5 (13,145) | 0.19 | Mann–Whitney U Test |
| AST/ALT | 0.92 ± 0.39 | 1.40 ± 0.54 | <0.001 | t test |
| Albumin | 4.5 ± 0.46 | 3.29 ± 0.7 | <0.001 | t test |
| INR | 1.07 ± 0.231 | 1.08 ± 0.236 | 0.62 | t test |
| NFS | −3.13 (−5.7,0.66) | 1.4 (−3.33, 4.44) | <0.001 | Mann–Whitney U Test |
| FIB-4 | 0.67 (0.17, 5.21) | 5.03 (0.56, 17.5) | <0.001 | Mann–Whitney U Test |
Abbreviations: ALT = alanine aminotransferase; AST = aspartate aminotransferase; BMI = body mass index; DM; FIB-4 = Fibrosis Score 4; INR = Indian rupee; NFS = non-alcoholic fatty liver disease (NAFLD) Fibrosis Score.