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. 2024 Apr 17;11:1385720. doi: 10.3389/fmed.2024.1385720

TABLE 2.

AD severity assessment at baseline and follow-up after 1 and 4 months on upadacitinib therapy.

Indicator Baseline
(n = 16)
1-month follow-up
(n = 16)
4-month follow-up
(n = 10)
EASI score
Median (min-max)
Mean (SD)

28.2 (10.6–60.5)
29.5(14.5)

10.1 (0–22.2)
10.7 (7.6)

2.15 (0–25.5)
5.5 (8.2)
DLQI
Median (min-max)
Mean (SD)

20.5 (4–29)
19.8 (6.7)

7.5 (0–23)
10.1 (8.0)

4 (0–20)
4.5 (5.9)
BSA
Median (min-max)

60 (32–95)

N/A

N/A
NRS-itch
Median (min-max)
Mean (SD)

9 (5–10)
8.5 (1.6)

2 (0–8)
3.1 (2.9)

N/A
NRS-insomnia
Median (min-max)
Mean (SD)

7 (0–10)
6.5 (3.5)

1 (0–7)
2.3 (2.8)

N/A

EASI, Eczema Area and Severity Index; SCORAD, Scoring of Atopic Dermatitis; DLQI, Dermatology Life Quality Index; vIGA-AD, Validated Investigator Global Assessment for AD; BSA, body surface area; NRS, numerical rate scale; SD, standard deviation; N/A, not accessed.