Table 1.
Characteristics of COVID-19 patients.
| Disease Status |
Total (N) |
Breakthrough (N) |
Age
a
(years) |
Sex (% males) |
CD3 a (cells/μL) | B cell a (cells/μL) | DSOa,b |
|---|---|---|---|---|---|---|---|
| Mild | 63 | 17 | 52 (38–62) | 54 | 941 (654–1,149) | 130 (88–216) | 9 (6–13) |
| Mod + Sev | 22 | 0 | 56 (48–67) | 50 | 803 (478–1,424) | 190 (87–333) | 10 (8–15) |
| All acute | 85 | 17 | 55 (42–63) | 52 | 920 (639–1,155) | 145 (87–234) | 9 (6–13) |
| Convalescent | 37 | 17 | 51 (35–56) | 41 | 1,209 (1,030–1,678) | 188 (149–246) | 66 (49–82) |
| Flu | 7 | 0 | 32 (26–33) | 14 | Not available | Not available | 3 (3–4) |
| HD | 20 | Not apply | 53 (35–58) | 80 | Not available | Not available | Not apply |
| p-value c | 0.0013 d | 0.4180 | 0.0006 e | 0.0537 | 0.0006 f |
Median days between acute and convalescent samples is 58 (IQR range 39-70).
a
Medians (IQR).
b
Days post symptom onset.
c
Groups were compared using Kruskal–Wallis test followed by Dunn’s multiple comparisons test, except when looking at sex differences, where we used Fisher’s exact test. The group “all acute” was not included in the comparisons because its patients were included in mild or Mod + Sev groups.
d
Flu group was significantly different from the Mild and Mod + Sev groups.
e
Convalescent group was significantly different from the Mild and Mod + Sev groups.
f
Convalescent group was not included in the comparisons. Flu group was significantly different from the Mild and Mod + Sev groups.