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. 2024 Apr 17;15:1362537. doi: 10.3389/fimmu.2024.1362537

Table 2.

Surface under the cumulative ranking (SUCRA) value on various treatments with SCLC.

Durvalumab Atezolizumab Nivolumab Pembrolizumab Ipilimumab Durvalumab+Tremelimumab Chemotherapy Nivolumab+Ipilimumab Serplulimab Adebrelimab
OS 75.37% 63.84% 20.17% 54.52% 35.90% 28.81% 30.13% 22.21% 94.02% 75.00%
PFS 46.47% 39.50% 14.72% 57.16% 60.13% 41.86% 53.75% 49.55% 79.41% 57.45%
DOR 45.35% 32.16% 78.76% - 57.10% - 21.47% 50.95% 64.20% -
SOR 77.81% 33.40% 73.22% 58.44% 29.29% - 26.77% 40.81% 60.25% -
Brain metastases 63.05% 38.35% 62.45% - 12.52% 51.60% 42.08% - 79.97% -
Without brain metastases 55.66% 67.58% 39.56% - 22.40% 48.27% 20.43% - 77.33% 68.77%
AE grade≥3 53.73% 52.62% 71.25% - 53.34% 43.23% 54.38% 23.10% 46.71% 51.61%
Decreased appetite 63.63% 2.64% 89.66% 86.11% 36.37% 43.53% 65.25% 18.02% - 44.77%
Anemia 48.45% 66.45% 99.08% 37.48% 37.85% 43.75% 37.23% 42.02% 47.99% 39.69%
Diarrhea 72.17% 50.68% 0.04% 76.66% 41.06% 61.11% 80.16% 18.13% - -
Pruritus 68.33% 46.04% 12.18% 76.25% 42.63% 68.13% 66.43% 20.01% - -
Fatigue 70.79% 44.38% 84.78% 41.62% 17.68% 75.61% 50.11% 15.03% - -
Nausea 75.40% 73.99% 62.41% 59.88% 59.70% 53.87% 52.66% 49.33% 6.53% 6.24%

Che, chemotherapy; Ate, Atezolizumab; Dur, Durvalumab; DurplusTre, Durvalumab + Tremelimumab; Ipi, Ipilimumab; Pem, Pembrolizumab; Ser, Serplulimab; Niv, Nivolumab; NivplusIpi, Nivolumab + Ipilimumab; Ade, Adebrelimab. PFS, progression-free survival; OS, overall survival; DOR, duration of response; SOR, stable of response; AE grade ≥ 3, adverse events of grade ≥ 3.