Figure 2.

Neutralization activity against the WT- and Omicron-derived variants, and anti-RBD antibody levels at the acute phase of COVID-19, and associations with pneumonia or hypoxemic respiratory failure in vaccinated (n = 47) and unvaccinated patients (n = 20). The Mann-Whitney test was used to compare values between vaccinated patients with (n = 16) and without pneumonia (n = 31), vaccinated patients with (n = 7) and without hypoxemic respiratory failure (n = 40), unvaccinated patients with (n = 9) and without pneumonia (n = 11), and unvaccinated patients with (n = 2) and without hypoxemic respiratory failure (n = 18). Each level was measured at admission (within 5 days after symptom onset) and each dot represents an individual value. Bars indicate medians with interquartile ranges. WT, wild-type; RBD, receptor-binding domain; *P<0.05; **P<0.01; ns, not significant.