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CWRES (conditional weighted residuals) vs time plot for fosfomycin. Values of CWRES should be approximately N (0, 1) and hence concentrated between y=−3 and y=+3. Inspection of the figure indicates that data were evenly distributed about zero and that the trends (as given by the blue line and the red line, its negative reflection) did not show any fanning, indicating no bias in the structural model.
