Fig. 5.

Probability of Target Attainment (PTA%) vs. minimal inhibitory concentration (MIC) (µg/mL) of fosfomycin for repeated administration of fosfomycin 20 mg/kg BW different dosing intervals ranging from 8 to 24 hr. Values were obtained from 5,000 simulated fosfomycin concentrations profiles generated from the population model by Monte Carlo simulations. PTA 90% is indicated by the solid blue line, which is considered as the target to achieve, and MIC that corresponds to PTA 90% is indicated by the dotted blue line.