Fig. 4.

(A) Schematic diagram of the treatment and test schedule of PD mice. (B) Time on rotarod in rotarod test, (C) the peak grip in grip test, (D) the immobility time in tail suspension test, (E) floating time in forced swimming test and (F) total time in pole test of mice after different treatments. (G) Representative paths of mice from different groups and (H) temporal heat map, (I) percentage of time in central zone, (J) average speed, (K) percentage of immobility time, and (L) rated zone crossing in the open field test of mice in different groups. For B–F and I-L, n = 6 for each group or measurement, ns for no significance, * for p < 0.05, ** for p < 0.01, *** for p < 0.001, respectively.