Table 4.
Subgroup | MIMIC-IV | eICU-CRD | ||||
---|---|---|---|---|---|---|
HR(95% CI) | P value |
P for interaction |
HR(95% CI) | P value |
P for interaction |
|
All patients | 1.63 (1.20,2.22) | 0.002 | 1.27 (1.04,1.59) | 0.038 | ||
Age | < 0.001 | < 0.001 | ||||
> 60 years | 2.38 (1.38,4.46) | 0.016 | 1.49 (1.13,1.86) | 0.029 | ||
≤ 60 years | 1.55 (0.88,2.41) | 0.085 | 1.05 (0.70,1.58) | 0.806 | ||
Diabetes | 0.002 | 0.008 | ||||
Yes | 1.64 (0.86, 2.82) | 0.374 | 1.06 (0.78, 1.52) | 0.066 | ||
No | 2.59 (1.06, 6.35) | 0.005 | 1.48 (1.12, 2.66) | 0.005 | ||
Hypertension | 0.039 | 0.520 | ||||
Yes | 2.17 (1.36,3.46) | 0.001 | 1.32 (1.03,1.86) | 0.008 | ||
No | 1.76 (0.92,3.36) | 0.085 | 1.22 (0.90,1.65) | 0.121 |
aSensitivity analysis was conducted by the Cox proportional regression model
bCox regression model was adjusted for age, gender, GCS, hypertension, congestive heart failure, WBC, serum creatinine, serum BUN, serum bilirubin, serum AST, PT, anticoagulant agents, and antiplatelet agents