Table 6.
Effects of arginine and its metabolites (NO and polyamine) on cell cycle
| Cell cycle | 0.4mM Arg | 0.4mM Arg + 3mM L-NMMA |
0.4mM Arg + 3mM L-NMMA + 0.5mM SNP |
0.4mM Arg + 5mM DFMO |
0.4mM Arg + 5mM DFMO + 10 µM Putrescine |
|
|---|---|---|---|---|---|---|
| d 2 | ||||||
| G1 | 33.37 ± 0.33bc | 42.16 ± 0.74a | 23.19 ± 0.91c | 33.72 ± 0.69bc | 32.53 ± 0.22bc | |
| S | 56.43 ± 0.85a | 37.89 ± 0.95c | 46.83 ± 0.68b | 54.35 ± 0.39a | 55.40 ± 0.71a | |
| G2 | 10.20 ± 1.17c | 19.95 ± 0.66b | 29.98 ± 1.33a | 11.93 ± 0.84c | 12.08 ± 0.70c | |
| d 4 | ||||||
| G1 | 42.05 ± 0.66 | 42.96 ± 1.45 | 36.32 ± 0.73 | 43.15 ± 1.06 | 42.02 ± 1.10 | |
| S | 37.40 ± 0.77 | 34.54 ± 0.76 | 36.24 ± 1.15 | 37.48 ± 0.50 | 39.57 ± 0.62 | |
| G2 | 20.55 ± 1.02 | 22.50 ± 1.16 | 27.44 ± 1.09 | 19.38 ± 0.59 | 18.41 ± 0.49 |
SEM, standard error of the mean (n = 4). a, b,c means within a row with different superscripts indicate significant