Table 4. Diagnostic values of SYPL1 and other variables in breast cancer.

PPV: Positive predictive value<br>NPV: Negative predictive value<br>SEAUC: Standart error<br>AUC: Area under the ROC curve

Variables	Cut-off	AUC	Sensitivity	Specificity	PPV	NPV	p
SYPL1	>12.26	0.639±0.047	48.75 [37.4–60.2]	80.56 [69.5–88.9]	73.6 [59.7–84.7]	58.6 [48.2–68.4]	0.002
CEA	>1.32	0.607±0.048	75 [64.1–84.0]	47.89 [35.9–60.1]	61.9 [51.4–71.5]	63.0 [48.7–75.7]	0.020
CA-15-3	>13.99	0.668±0.046	80 [66.8–86.1]	49.30 [39.9–64.1]	64.6 [54.2–74.1]	67.3 [53.3–79.3]	<0.001
CA15-3+SYPL1			32.5	87.5	74.29	53.85