Table 5. Changes in metabolic indexes of obese PCOS patients (22 cases) taking metformin for 3 months.
| Before drug administration<br>(n=22) | 3 months of medication<br>(n=22) | t | P | |
|---|---|---|---|---|
| Body weight (kg) | 798±11.4 | 74.8±11.4 | 1.441 | 0.157 |
| BMI (kg/cm2) | 31.2±4.8 | 29.2±5.0 | 1.273 | 0.210 |
| Waist circumference (cm) | 99.0±11.7 | 95.1±10.9 | 1.133 | 0.264 |
| Hip circumference (cm) | 103.6±7.4 | 101.2±10.9 | 1.108 | 0.274 |
| WHR waist/hip | 0.9±0.1 | 0.9±0.1 | 0.798 | 0.429 |
| FPG (mmol/L) | 6.4±1.9 | 5.6±0.7 | 1.769 | 0.085 |
| INS (mmol/L) | 27.8±14.5 | 20.7±8.9 | 2.455 | 0.016 |
| HOMA-IR | 8.4±6.9 | 5.2±2.6 | 1.907 | 0.044 |
| TC (mmol/L) | 4.6±0.6 | 4.68±0.67 | -0.240 | 0.812 |
| TG (mmol/L) | 1.6±0.6 | 1.8±0.8 | -1.093 | 0.281 |
| HDL (mmol/L) | 1.2±0.2 | 1.3±0.5 | -1.077 | 0.288 |
| LDL (mmol/L) | 2.9±0.6 | 2.9±0.65 | 0.310 | 0.292 |
| Apo-B (g/L) | 0.9±0.4 | 1.0±0.2 | -1.434 | 0.159 |
| FSH (IU/L) | 5.0±1.6 | 5.0±1.6 | -0.016 | 0.987 |
| LH (IU/L) | 7.9±4.9 | 6.5±3.8 | 1.111 | 0.273 |
| LH/FSH | 1.5±0.7 | 1.3±0.7 | 0.903 | 0.372 |
| T (nmol/L) | 1.0±0.6 | 0.7±0.4 | 2.001 | 0.038 |