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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: J Urol. 2023 Feb 27;209(6):1132–1140. doi: 10.1097/JU.0000000000003394

Table 3.

ROC-based Thresholds for Pelvic Pain Severity and Urinary Symptom Severity using ‘Markedly Improved’ as the Definition of Responder

Absolute Change Percent Change Attained Score
CID AUC CID AUC CID AUC
PPS Subgroup Overall −4 0.75 −30 0.76 10 0.80
Sex-Diagnosis Male CP/CPPS Only −3 0.69 −25 0.66 9 0.76
Male with IC/BPS −2 0.68 −10 0.67 12 0.76
Female −5 0.78 −30 0.80 10 0.83
Hunner Lesions Yes −6 0.91 −30 0.91 10 0.87
No −4 0.78 −30 0.80 10 0.83
PainDETECT Type Likely Neuropathic −7 0.90 −40 0.90 12 0.86
Likely Non-neuropathic −4 0.71 −25 0.70 9 0.75
Most Bothersome Symptom Type PPS Bother −4 0.77 −20 0.78 11 0.83
USS Bother −4 0.68 −35 0.70 9 0.72
Widespreadness Widespread −5 0.82 −25 0.82 11 0.80
Localized −4 0.69 −30 0.71 8 0.80
Baseline Tertile Low tertile −1 0.57 −10 0.58 7 0.68
Middle Tertile −5 0.84 −35 0.85 10 0.86
High Tertile −9 0.95 −40 0.94 14 0.93
USS Subgroup Overall −2 0.68 −20 0.71 8 0.69
Sex-Diagnosis Male CP/CPPS Only −2 0.64 −20 0.62 6 0.53
Male with IC/BPS 0 0.35 7 0.34 10 0.55
Female −3 0.76 −25 0.80 8 0.77
Hunner Lesions Yes −1 0.61 −4 0.64 11 0.67
No −2 0.69 −20 0.72 8 0.74
PainDETECT Type Likely Neuropathic −3 0.81 −30 0.81 9 0.74
Likely Non-neuropathic −2 0.66 −20 0.69 8 0.67
Most Bothersome Symptom Type PPS Bother −3 0.76 −30 0.79 6 0.76
USS Bother −2 0.66 −15 0.68 11 0.66
Widespreadness Widespread −3 0.71 −20 0.75 9 0.73
Localized −2 0.66 −20 0.68 6 0.65
Baseline Tertile Low tertile −1 0.69 −15 0.68 5 0.59
Middle Tertile −4 0.83 −30 0.84 8 0.84
High Tertile −3 0.71 −20 0.71 15 0.72