Table 3.

ROC-based Thresholds for Pelvic Pain Severity and Urinary Symptom Severity using ‘Markedly Improved’ as the Definition of Responder

			Absolute Change		Percent Change		Attained Score
			CID	AUC	CID	AUC	CID	AUC
PPS	Subgroup	Overall	−4	0.75	−30	0.76	10	0.80
	Sex-Diagnosis	Male CP/CPPS Only	−3	0.69	−25	0.66	9	0.76
		Male with IC/BPS	−2	0.68	−10	0.67	12	0.76
		Female	−5	0.78	−30	0.80	10	0.83
	Hunner Lesions	Yes	−6	0.91	−30	0.91	10	0.87
		No	−4	0.78	−30	0.80	10	0.83
	PainDETECT Type	Likely Neuropathic	−7	0.90	−40	0.90	12	0.86
		Likely Non-neuropathic	−4	0.71	−25	0.70	9	0.75
	Most Bothersome Symptom Type	PPS Bother	−4	0.77	−20	0.78	11	0.83
		USS Bother	−4	0.68	−35	0.70	9	0.72
	Widespreadness	Widespread	−5	0.82	−25	0.82	11	0.80
		Localized	−4	0.69	−30	0.71	8	0.80
	Baseline Tertile	Low tertile	−1	0.57	−10	0.58	7	0.68
		Middle Tertile	−5	0.84	−35	0.85	10	0.86
		High Tertile	−9	0.95	−40	0.94	14	0.93
USS	Subgroup	Overall	−2	0.68	−20	0.71	8	0.69
	Sex-Diagnosis	Male CP/CPPS Only	−2	0.64	−20	0.62	6	0.53
		Male with IC/BPS	0	0.35	7	0.34	10	0.55
		Female	−3	0.76	−25	0.80	8	0.77
	Hunner Lesions	Yes	−1	0.61	−4	0.64	11	0.67
		No	−2	0.69	−20	0.72	8	0.74
	PainDETECT Type	Likely Neuropathic	−3	0.81	−30	0.81	9	0.74
		Likely Non-neuropathic	−2	0.66	−20	0.69	8	0.67
	Most Bothersome Symptom Type	PPS Bother	−3	0.76	−30	0.79	6	0.76
		USS Bother	−2	0.66	−15	0.68	11	0.66
	Widespreadness	Widespread	−3	0.71	−20	0.75	9	0.73
		Localized	−2	0.66	−20	0.68	6	0.65
	Baseline Tertile	Low tertile	−1	0.69	−15	0.68	5	0.59
		Middle Tertile	−4	0.83	−30	0.84	8	0.84
		High Tertile	−3	0.71	−20	0.71	15	0.72