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. 2024 May 1;10(18):eadj0604. doi: 10.1126/sciadv.adj0604

Fig. 8. Histopathology analysis.

Fig. 8.

(A) Schematic diagram of the analysis of inflammatory factors in blood samples by ELISA. (B) Pro-inflammatory and (C) anti-inflammatory factors in blood. (D) Schematic diagram of the analysis of inflammatory factors in synovium. (E) Pro-inflammatory and (F) anti-inflammatory factors in synovium tissue. (G) hematoxylin and eosin staining of the bone-synovial tissue. Scale bars, 100 μm. Synovial IHC analyses of the expression of (H) CD86 and (I) CD206. Scale bars, 100 μm. (J) 3D reconstructions of bone tissue via micro–computed tomography of right hind paws. Scale bar, 5 mm. (K) Bone analysis (trabecular bone ratio, bone volume fraction, bone density, and trabecular separation/spacing). ES, electrical stimulation. Data are means ± SD (n = 4). *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.