Table 3.
low CAA-SVD score (n = 11) | high CAA-SVD score (n = 32) | p | |
---|---|---|---|
Age, y, mean±SD | 81.2±6.1 | 74.8±8.4 | 0.025∗ |
Male, n (%) | 4 (36.4) | 14 (43.8) | 0.736 |
MMSE, median (IQR) | 20 (18–23) | 24 (19–26) | 0.356 |
Hypertension, n (%) | 5 (45.5) | 14 (43.8) | 1 |
Diabetes mellitus, n (%) | 2 (18.2) | 5 (15.6) | 1 |
Dyslipidemia, n (%) | 7 (38.9) | 15 (42.9) | 1 |
Smoking, n (%) | 3 (27.3) | 7 (21.9) | 0.698 |
HA-SVD-Score, median (IQR) | |||
Lacune | 0 (0–1) | 1 (1–1) | 0.483 |
CMBs | 1 (1–1) | 1 (1–1) | 1 |
BG-PVS | 1 (1–1) | 1 (1–1) | 0.880 |
WMH | 1 (0–1) | 1 (1–1) | 0.386 |
Total | 3 (3–4) | 4 (3–4) | 0.154 |
CAA-SVD-Score, median (IQR) | |||
Lobar CMBs | 0 (0–1) | 2 (2–2) | <0.001∗ |
cSS | 0 (0–0) | 0 (0–0) | 0.555 |
CSO-PVS | 0 (0–1) | 1 (0–1) | 0.117 |
WMH | 1 (0–1) | 1 (1–1) | 0.386 |
Total | 2 (1–2) | 4 (3–4) | <0.001∗ |
BG, basal ganglia; CAA, cerebral amyloid angiopathy; CMB, cerebral microbleed; CSO, centrum semiovale; cSS, cortical superficial siderosis; HA, hypertensive arteriopathy; IQR, interquartile range; MMSE, Mini-Mental State Examination; PVS, perivascular space; SD, standard deviation; SVD, small vessel disease; WMH, white matter hyperintensity.
p < 0.05 for low CAA-SVD score versus high CAA-SVD score.