Table 2.

Vaginal dysbiosis (VD) – relative risk on reproductive outcomes

Outcome	RR (CI 95%)	No. of participants (studies)
Primary outcomes
Live birth rate (CST IV)	0.94 (0.76–1.16)	4605 (14)
Live birth rate (BV)	0.96 (0.76–1.21)	4359 (13)
Microscopy	1.02 (0.75–1.40)	3776 (8)
Molecular	0.76 (0.51–1.13)	658 (6)
Early pregnancy loss (CST IV)	1.49 (1.15–1.94)	3153 (20)
Early pregnancy loss (BV)	1.62 (1.26–2.08)	3045 (19)
Microscopy	1.51 (1.16–1.96)	2792 (14)
Molecular	2.35 (1.36–4.07)	291 (6)
Secondary outcomes
Clinical pregnancy rate (CST IV)	0.82 (0.70–0.95)	6550 (25)
Clinical pregnancy rate (BV)	0.85 (0.71–1.01)	6092 (22)
Microscopy	0.85 (0.69–1.05)	5488 (16)
Molecular	0.81 (0.61–1.07)	781 (8)
Biochemical pregnancy rate (CST IV)	0.95 (0.82–1.10)	5455 (17)
Biochemical pregnancy rate (BV)	0.95 (0.82–1.10)	5455 (17)
Microscopy	0.98 (0.82–1.17)	4938 (13)
Molecular	0.78 (0.59–1.02)	601 (5)

BV, bacterial vaginosis; CI, confidence interval; CST, community state type; RR, relative risk.