Figure 5.

Polygenic risk score for LVESVi: violin plots showing the distribution of LVESVi-PRS in athletes with a reduced or normal EF, in comparison with a healthy elderly population from the ASPREE study⁶ and patients with established DCM. Mean LVESVi-PRS in athletes with reduced EF is higher than in control subjects and athletes with normal EF, but similar to patients with DCM. Data for mean ± interquartile range in each group are shown. ASPREE indicates Aspirin in Reducing Events in the Elderly; DCM, dilated cardiomyopathy; EF, ejection fraction; LVESVi, indexed left ventricular end-systolic volume; and PRS, polygenic risk score.